Tri-Heart Plus vs Advantage Multi

There’s one thing pet parents can agree on - it’s essential that your dog stays happy and healthy. That’s why it’s so important to protect your dog against fleas, ticks, and heartworms. Tri-Heart Plus and Advantage Multi are two of the best-loved options among veterinarians and dog parents. It may be difficult to discern the differences between all the product options available today, but we’ve assembled a table and some details below that can help you make the best decision for your dog.

Tri-Heart Plus for Dogs

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Save $5 off $50
with coupon code COMPARE5

What are the key differences between Tri-Heart Plus and Advantage Multi?

First, let’s talk about the similarities between these two products. The first thing these medications have in common is that they both protect your dog against heartworms, roundworms, and hookworms. They are both prescription-only formulas, and they are both administered monthly. The final similarity between these formulas is that they are both safe for use in puppies. Tri-Heart Plus can be safely administered to puppies as young as 6 weeks old, while Advantage Multi is safe for use in puppies 7 weeks and older weighing a minimum of 3 pounds.

Now, we’ll discuss the many differences between Tri-Heart Plus and Advantage Multi. One key difference between these treatment options are their modes of administration. Tri-Heart Plus is a beef-flavored chewable tablet, and Advantage Multi is a topical formula. They also contain different active ingredients. Tri-Heart Plus uses Ivermectin and Pyrantel Pamoate to combat parasites, while Advantage Multi contains Moxidectin and Imidacloprid.

Tri-Heart Plus is safe for use in breeding or pregnant dogs. Prior to using Advantage Multi on a breeding, pregnant, or lactating dog, you should speak to your veterinarian. Advantage Multi also offers added protection against two other parasites - it kills ear mites and fleas.

Choosing between Tri-Heart Plus and Advantage Multi

With this information in mind, it’s time to decide which product you’d like to discuss with your veterinarian. A few considerations can be helpful in your decision. Firstly, neither product is safe for use in cats. However, if you’re searching for the best heartworm preventative for your cat, Advantage Multi for Cats might be a great option for your feline friend.

If you’re planning to treat a pregnant or breeding dog, Tri-Heart Plus might be the best choice. If you’re hoping to protect your dog against fleas and ear mites, Advantage Multi is a great way to do so. Advantage Multi is ideal for pet parents who prefer topical application, while Tri-Heart Plus is a great choice for those who like to administer oral medications instead.

Be sure to speak to your veterinarian about protecting your dog against heartworms and other dangerous parasites. He or she can answer all your questions and address any concerns you may have. From there, it’s time to get a prescription! Be sure to come to GiantEaglePetRx for the lowest prices on all of your dog’s medications. If you have any further questions on these products or on anything else GiantEaglePetRx sells, reach out for a pet parent consultation!

Feature Tri-Heart Plus Advantage Multi
Kills Fleas No Yes
Repels Fleas No No
Kills Flea Eggs and Larvae No No
Kills Ticks No No
Repels Ticks No No
Repels Mosquitoes No No
Prevents Heartworm Yes Yes
Other Parasites Hookworms and Roundworms Ear mites, Roundworms, Hookworms and Tapeworms.
Waterproof Yes since taken orally Yes
How Long to work N/A N/A
Taste Beef Flavored N/A
Active Ingredient Ivermectin and Pyrantel Pamoate Imidacloprid and Moxidectin
RX Required Yes Yes
Application Type Chewable Tablet Topical
Dosing 1 tablet per month 1 application per month
Age Dogs ages 6 weeks and older Dogs 7 weeks and older that weigh 3 lbs or more
Manufacturer Merck Animal Health Bayer Animal Health
Safety Safe for pregnant or breeding females. Speak to your vet about risks associated with breeding, pregnant, or lactating dogs