Advantage Multi vs Heartgard Plus

As a pet parent, your dog’s health is your primary concern. Picking the best flea and/or parasite treatment is essential. plays a critical role in keeping your pet protected, happy, and healthy. Advantage Multi and Heartgard Plus are a couple of the most popular products. Each effective and dependable product offers its own advantages. They are also very different from one another. See below to learn how they compare!

Advantage Multi for Dogs

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What are the key differences between Advantage Multi and Heartgard Plus?

One of several notable differences between these treatments is that Advantage Multi is a topical product, while Heartgard Plus is a chewable tablet. Each medication is administered monthly, and they are both safe for use in puppies (Heartgard Plus from an age of 6 weeks, and Advantage from 7 weeks and 3 pounds).

Heartgard Plus is proven safe for use in breeding or pregnant female dogs. If you’re considering Advantage Multi for your pregnant, breeding, or lactating dog, you should consult your veterinarian. Both products are available only with a prescription from a veterinarian.

Advantage Multi contains Moxidectin and Imidacloprid, which team up to kill fleas, prevent heartworm disease, and combat hookworms, roundworms, and ear mites. It begins killing fleas within 12 hours.

Heartgard Plus uses Pyrantel Pamoate and Ivermectin to prevent heartworm disease, roundworms, and hookworms. It offers a tasty beef flavor.

How do I choose between Advantage Multi and Heartgard Plus?

Your decision might be as simple as deciding between an oral treatment or a topical one. It might come down to whether or not your dog is pregnant, breeding, or lactating. If you prefer a topical treatment, Advantage Multi is a great choice. If your dog would do best on an oral medication, you might choose Heartgard Plus.

You’ll also want to decide what parasite protection is most important for your dog. For protection against roundworms, hookworms, and heartworms, Heartgard Plus is an ideal option. For protection against fleas, hookworms, roundworms, ear mites, and heartworms, you’ll want to opt for Advantage Multi.

Feature Advantage Multi Heartgard Plus
Kills Fleas Yes No
Repels Fleas No No
Kills Flea Eggs and Larvae No No
Kills Ticks No No
Repels Ticks No No
Repels Mosquitoes No No
Prevents Heartworm Yes Yes
Other Parasites Ear mites, roundworms, and hookworms Hookworms and roundworms
Waterproof Yes Yes
How Long to work Begins to kill fleas within 12 hours N/A
Taste N/A Beef flavored
Active Ingredient Imidacloprid and Moxidectin Ivermectin and Pyrantel Pamoate
RX Required Yes Yes
Application Type Topical Chewable Tablet
Dosing 1 application per month 1 tablet per month
Age Dogs 7 weeks and older that weight at least 3 pounds Dogs 6 weeks and older
Manufacturer Bayer Animal Health Boehringer Ingelheim
Safety Speak to your vet about risks associated with breeding, pregnant, or lactating dogs Safe for pregnant or breeding females.