Tri-Heart Plus vs Heartgard Plus

A pet parent’s primary concerns are their dog’s health and happiness. That’s why heartworm prevention is so important. Tri-Heart Plus and Heartgard Plus are two of the most popular treatment options available today. Both of these products are safe, dependable, and effective. So how do they compare? Keep reading to find out more!

Tri-Heart Plus for Dogs

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Save $5 off $50
with coupon code COMPARE5

What are the differences between Tri-Heart Plus and Heartgard Plus?

You may be surprised to find that these two top-of-the-line medications are more similar than they are different. These parallels are all thanks to the two active ingredients in the formulas - Pyrantel Pamoate and Ivermectin. Both products share the same ingredients, making them equally effective against heartworms, hookworms, and roundworms. 

Tri-Heart Plus and Heartgard Plus are available only with a prescription, and they are administered monthly. Both products are safe for use in pregnant or breeding dogs, and they can also be safely administered to puppies ages 6 weeks and up.

One key difference between these medications is that Tri-Heart Plus comes in the form of a chewable, beef-flavored tablet, while Heartgard Plus is a soft, beefy chew. You may have also noticed that Tri-Heart Plus is a more affordable option than Heartgard Plus.

How do I choose between Tri-Heart Plus and Heartgard Plus?

For many pet parents, the decision between these two medications simply comes down to the dog’s preferences. Some dogs are incredibly picky, preferring a soft chew like Heartgard Plus over a chewable tablet like Tri-Heart Plus. Other people may base their decision on cost. In this case, you’ll probably choose Tri-Heart Plus. If you’re searching for a treatment option for your cat, take a look at the cat-safe Heartgard for Cats.

Now that you’ve brushed up on your options, it’s a great idea to make a veterinarian appointment for your pup. You’ll want to discuss the product you’ve chosen and confirm whether or not your vet believes it to be the best choice for your specific pet. If you find yourself with any other product questions, reach out to the GiantEaglePetRx pharmacists for a free pet parent consultation!

Feature Tri-Heart Plus Heartgard Plus
Kills Fleas No No
Repels Fleas No No
Kills Flea Eggs and Larvae No No
Kills Ticks No No
Repels Ticks No No
Repels Mosquitoes No No
Prevents Heartworm Yes Yes
Other Parasites Hookworms and Roundworms Hookworms and Roundworms
Waterproof Yes since taken orally Yes
How Long to work N/A N/A
Taste Beef Flavored Beef Flavored
Active Ingredient Ivermectin and Pyrantel Pamoate Ivermectin and Pyrantel Pamoate
RX Required Yes Yes
Application Type Chewable Tablet Soft Chew
Dosing 1 tablet per month 1 soft chew per month
Age Dogs ages 6 weeks and older Dogs 6 weeks and older
Manufacturer Merck Animal Health Boehringer Ingelheim
Safety Safe for pregnant or breeding females. Safe for pregnant or breeding females.