Advantage Multi vs Sentinel

Choosing a parasite treatment is an essential part of protecting your dog against troublesome and even detrimental pests. Two of the most-loved and best-known options are Advantage Multi and Sentinel. Each of these high-quality products offer unique advantages, which are detailed below to help you pick the ideal treatment for your pet.

Advantage Multi for Dogs

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Save $5 off $50
with coupon code COMPARE5

What makes Advantage Multi different from Sentinel?

First, let’s highlight the parallels between these medications. One key similarity is that both Advantage Multi and Sentinel require a prescription from a veterinarian. They are also both effective against heartworm, roundworm, and hookworm. They are each administered monthly. Finally, they are both safe for use in puppies. Advantage Multi can be used in puppies 7 weeks and older weighing at least 3 pounds, and Sentinel is safe for puppies from an age of 4 weeks.

Now that we’ve addressed the similarities between these two products, it’s time to compare the differences. One key dissimilarity is that Advantage Multi is a topical treatment, while Sentinel is an oral one. Sentinel is safe for use in breeding, lactating, or pregnant dogs, but Advantage Multi should only be used in these dogs when a veterinarian has deemed it safe and necessary.

Advantage Multi combines Moxidectin and Imidacloprid to combat the aforementioned parasites, along with fleas and ear mites. It starts killing fleas within 12 hours. Sentinel uses Lufenuron and Milbemycin Oxime to kill the pests listed in the first paragraph. It also controls whipworms and breaks the life cycle of the flea by killing flea eggs and larvae. Sentinel is not effective against existing infestations, while Advantage Multi is used to gain control of existing infestations.

How do I make the choice between Advantage Multi and Sentinel?

Determining your dog’s needs is the best way to make this important decision. If your dog is suffering from an existing flea infestation, Advantage Multi is the ideal way to eradicate that problem. If not, Sentinel might be a good option. If your dog is pregnant, lactating, or breeding, the safest treatment option may be Sentinel. If you have a very young puppy (between the ages of 4 weeks and 7 weeks), Sentinel is an excellent choice.

If whipworms are a concern, Sentinel might be the best way to tackle that issue. If ear mites are plaguing your dog, you might opt for Advantage Multi. If you’re still undecided, your choice might simply come down to your own preferences. If you’d like to administer an oral medication each month, Sentinel is the clear winner. If you would rather go for a topical treatment, Advantage Multi is the way to go.

Now that you’ve brushed up on these two incredible treatments, it’s time to consult with your veterinarian. Your vet will be able to address any concerns you have and answer all your questions. They’ll help you make the best decision for your individual dog. If you find yourself with any lingering questions, give the GiantEaglePetRx pharmacists a call! They are available to consult with pet parents about any medication or supplement.

Feature Advantage Multi Sentinel
Kills Fleas Yes No
Repels Fleas No No
Kills Flea Eggs and Larvae No Stops development
Kills Ticks No No
Repels Ticks No No
Repels Mosquitoes No No
Prevents Heartworm Yes Yes
Other Parasites Ear mites, roundworms, and hookworms Roundworms, Whipworms, and Hookworms
Waterproof Yes Yes since taken orally
How Long to work Begins to kill fleas within 12 hours Breaks cycle of fleas and eggs. Does not kill existing flea infestation.
Taste N/A Savory Beef
Active Ingredient Imidacloprid and Moxidectin Milbemycin Oxime and Lufenuron
RX Required Yes Yes
Application Type Topical Chewable Tablet
Dosing 1 application per month 1 tablet per month
Age Dogs 7 weeks and older that weight at least 3 pounds Dogs 4 weeks and older
Manufacturer Bayer Animal Health Virbac
Safety Speak to your vet about risks associated with breeding, pregnant, or lactating dogs Breeding, pregnant, and lactating dogs may use.