Sentinel Spectrum vs Heartgard Plus

Pet parents are constantly searching for ways to keep their dogs healthy and happy. Protecting your pup against dangerous parasites is an essential part of your role as a dog parent. Two of the most effective, safe, and well-liked options for parasite and heartworm prevention are Sentinel Spectrum and Heartgard Plus. While these formulas share a number of similarities, they are also different in many ways. Keep reading to learn about the differences that might help you choose one of these amazing products!

Sentinel Spectrum for Dogs

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Heartgard Plus

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What are the key differences between Sentinel Spectrum and Heartgard Plus?

First, let’s discuss the similarities between these two products. Both formulas protect dogs against dangerous parasites, such as heartworms, roundworms, and hookworms. Both medications are prescription-only, once-monthly treatments, and they are both safe for use in pregnant or breeding dogs. 

Both formulas are also safe for use in puppies over the age of 6 weeks old (although Sentinel Spectrum should only be administered to puppies weighing more than 2 pounds). Finally, they are both orally-administered medications. Sentinel Spectrum comes in the form of a chewable, beef-flavored tablet, while Heartgard Plus is a soft, savory, beef-flavored chew.

Each of these effective medications offer different active ingredients. Heartgard Plus contains Ivermectin and Pyrantel Pamoate, while Sentinel Spectrum offers a trio of Lufenuron, Milbemycin Oxime, and Praziquantel. With this combination of ingredients, Sentinel Spectrum offers added protection against whipworms. It also inhibits the development of flea eggs and larvae, and it is safe for use in lactating dogs.

While neither product is formulated for cats, Heartgard for Cats is a great choice for your feline friend.

Choosing between Sentinel Spectrum and Heartgard Plus

When you’re deciding between these two medications, ask yourself a few questions. First of all, do you have a lactating dog? If so, Sentinel Spectrum is the safest treatment option. Is your dog a finicky eater? If so, you might find that your pup prefers the taste of the beefy chew offered by Heartgard Plus. If you’re searching for a product that protects against fleas and whipworms, Sentinel Spectrum is an excellent choice.

Once you’ve decided which product sounds like the best option for your specific pet, it’s time to make an appointment with your veterinarian. Be sure to address any concerns you might have at this time, and don’t forget to bring your prescription to GiantEaglePetRx to get the lowest price on your dog’s medications! If you have questions that arise after you leave your vet’s office, give our licensed pharmacists a call. They are standing by to offer free pet parent consultations, and they are up to date on all the latest information about every GiantEaglePetRx product.

Feature Sentinel Spectrum Heartgard Plus
Kills Fleas No No
Repels Fleas No No
Kills Flea Eggs and Larvae Stops Development No
Kills Ticks No No
Repels Ticks No No
Repels Mosquitoes No No
Prevents Heartworm Yes Yes
Other Parasites whipworms, Hookworms, Roundworms and Tapeworms Hookworms and Roundworms
Waterproof Yes since taken orally Yes
How Long to work N/A N/A
Taste Beef Flavored Beef Flavored
Active Ingredient Milbemycin Oxime, Lufenuron, and Praziquantel Ivermectin and Pyrantel Pamoate
RX Required Yes Yes
Application Type Chewable Tablet Chewable Tablet
Dosing 1 tablet per month 1 tablet per month
Age Dogs aged 6 weeks and weight 2lbs or more Dogs 6 weeks and older
Manufacturer Merck Animal Health Boehringer Ingelheim
Safety Breeding, pregnant, and lactating dogs may use. Safe for pregnant or breeding females.