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Click on image to open expanded view Item No. 50764

Sileo Gel for Dogs (Dexmedetomidine Oromucosal) 0.09 mg/ml, 3 ml syringe Rx

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Product Description
Dexmedetomidine is included in Sileo Oromucosal Gel and is used to treat canine noise aversion. It is the only and first FDA-approved prescription therapy for noise aversion. This medicine helps the dog remain calm while engaging and behaving normally due to the low dexmedetomidine dosage.
Who is Sileo Gel for Dogs (Dexmedetomidine Oromucosal) 0.09 mg/ml, 3 ml syringe for?
Dogs must be 16 weeks or older.
Why use Sileo Gel for Dogs (Dexmedetomidine Oromucosal) 0.09 mg/ml, 3 ml syringe?
Sileo Features: Simple therapy that makes it easier to manage a difficult condition Demonstrated to be effective and safe in random, placebo-controlled clinical studies Acts quickly to calm dogs while maintaining normal relationships between canines and their owners Calms dogs but has no sedative properties Simple to use at home and works without the need for training or additional therapies
How does Sileo Gel for Dogs (Dexmedetomidine Oromucosal) 0.09 mg/ml, 3 ml syringe work?
Sileo works by inhibiting the neurotransmitter norepinephrine in the brain. This molecule works in a similar way to adrenaline because it accelerates anxiety.
Manufacturer:
Zoetis
Active Ingredients(s):
Dexmedetomidine Hydrochloride
How is Sileo Gel for Dogs (Dexmedetomidine Oromucosal) 0.09 mg/ml, 3 ml syringe sold?
Dexmedetomidine Oromucosal 0.09 mg/ml, 3 ml syringe
What are the side effects of Sileo Gel for Dogs (Dexmedetomidine Oromucosal) 0.09 mg/ml, 3 ml syringe?
In rare cases, side effects can occur. Side effects include: Sedation Drowsiness Vomiting (Emesis) Short-Term Application Site Mucous Membrane Paleness
What special precautions are there?
Never use this product in animals with: Bradycardia Hypoxia Hypotension Hypersensitivity to dexmedetomidine or any of the excipients Conditions of stress associated with extreme heat, extreme cold, or fatigue Conditions of shock or severe debilitation Kidney disease Liver disease Respiratory disease Severe cardiovascular disease Keep away from children. Not for human use. This product should not be used by pregnant women. Exposure can cause fetal blood pressure to decrease or uterine contractions to start. When handling or administering this product, and when coming into contact with a treated dog's mouth, use impermeable, disposable gloves. When using or handling a filled syringe, avoid direct contact with your lips, eyes, or skin. This product has not been proven safe for use in dogs with gingival or dental disease; dogs under 16 weeks old, or in lactating, breeding, or pregnant dogs. These conditions can alter absorption of the medication. Never give to a dog that has been sedated by the medication previously.
What to do if overdose?
If overdose occurs, please contact your local pet hospital or emergency pet clinic immediately.
How can I store Sileo Gel for Dogs (Dexmedetomidine Oromucosal) 0.09 mg/ml, 3 ml syringe?
Within 14 days of opening the syringe, use the product. Protect the product from light. Store between 68 and 77 degrees Fahrenheit (20 and 25 degrees Celsius). Excursions between 59 and 86 degrees Fahrenheit (15 and 30 degrees Celsius) are permissible.
Helpful Tips:
You can take any or all of these actions to change their home environment and relieve your dog's stress in addition to Sileo treatment: If your dog exhibits indications of noise aversion, consult a veterinarian. Never touch your dog or say "it's alright." During a noisy event, this will communicate the message that panting, pacing, and barking are acceptable responses. Never penalize a dog for property damage or an accident during a noisy event. This may make them even more frightened of the sound. It's important to remember that they're acting out of fear, not malice. When noise happens, act normally - for example, watch TV, read a book, or play with the dog. Be there to console your dog. Create a secure sanctuary for your dog in a soundproof bathroom, closet, or basement. To reduce visual stimulation during pyrotechnics, close the drapes and keep the room brightly lighted. Music can be used to mask disturbing noises. Classical music has been demonstrated to help dogs relax. Reduce or eliminate your exposure to frightening noises.
Overview
Dosing Recommendations: 4.4-12.1 Lbs: 0.25 mL 12.2-26.5 Lbs: 0.5 mL 26.6-44.0 Lbs: 0.75 mL 44.1-63.9 Lbs: 1 mL 64.0-86.0 Lbs: 1.25 mL 86.1-110.2 Lbs: 1.5 mL 110.3-137.8 Lbs: 1.75 mL 137.9-166.4 Lbs: 2 mL 166.5-196.2 Lbs: 2.25 mL 196.3-220.5 Lbs: 2.5 mL If the noise persists for more than 2 to 3 hours and fear or anxiety symptoms emerge, give extra doses a minimum of 2 hours apart. It is possible to deliver up to 5 doses during a single loud event. When the owner detects a fear or anxiety-inducing noise stimuli (such as fireworks or thunder), shortly after the first symptom of noise-related fear or anxiety, or about 30-60 minutes before a scheduled anxiety or fear-inducing noise stimulus begins, give the first dosage. Divide the dose across each side of the dog's mouth when providing a dose larger than 1.5mL. Sileo includes 0.1 mg dexmedetomidine hydrochloride per milliliter. Because this gel dissolves into the oral mucosa, it should not be eaten. The product may not be effective if consumed. If the dose is swallowed, wait at least 2 hours before administering another dose. 125mcg/m2 is the recommended dosage. Inject into the dog's oral mucosa between his or her gums and cheeks.
Main Ingredients
Dexmedetomidine Oromucosal 0.09 mg/ml, 3 ml syringe