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Item No.
52722
Zycosan (Pentosan Polysulfate Sodium Injection) 250 mg/mL, 7.5 mL vial Rx
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Product Description
Zycosan (Pentosan Polysulfate Sodium Injection) 250 mg/ml is indicated for the control of clinical signs associated with osteoarthritis in horses. *Sold as individual 7.5 ml vial.
Who is Zycosan (Pentosan Polysulfate Sodium Injection) 250 mg/mL, 7.5 mL vial for?
Horses
Why use Zycosan (Pentosan Polysulfate Sodium Injection) 250 mg/mL, 7.5 mL vial?
Pentosan Polysulfate is a useful treatment for osteoarthritis in horses.
How does Zycosan (Pentosan Polysulfate Sodium Injection) 250 mg/mL, 7.5 mL vial work?
Pentosan Polysulfate, or PPS, is a semi-synthetic polysaccharide ester that is similar to heparin. Derived from the hemicellulose of beechwood, PPS is considered a mild anticoagulant. It has hypolipidemic, fibrinolytic, and anti-inflammatory qualities. PPS is useful in managing and treating osteoarthritis. It is believed to aid in preserving the integrity of cartilage, improving the health of the joints by supporting the anabolic activity of synoviocytes and chondrocytes. It protects against catabolic events in the joints because it reduces cytokine levels and inflammatory mediators in the synovial fluid and cartilage matrix.
Manufacturer:
Dechra
Active Ingredients(s):
250 mg/mL Pentosan Polysulfate Sodium
How is Zycosan (Pentosan Polysulfate Sodium Injection) 250 mg/mL, 7.5 mL vial sold?
Sold as individual 7.5 ml vial
What are the side effects of Zycosan (Pentosan Polysulfate Sodium Injection) 250 mg/mL, 7.5 mL vial?
The most frequently reported adverse reactions are injection site reactions, prolongation of coagulation parameters (activated partial thromboplastin time (aPTT) and prothrombin time (PT).
What special precautions are there?
Keep away from children and animals. As with all drugs, side effects may occur. For intramuscular use in horses only. Not for use in humans. Pentosan polysulfate sodium is a weak anticoagulant. Caution should be used when administering Zycosan if you are taking an anticoagulant. In case of accidental self-injection, seek immediate medical attention. If product comes into contact with skin, rinse skin thoroughly with water and seek medical attention if needed. Horses with hypersensitivity to pentosan polysulfate sodium should not receive Zycosan. Do not use Zycosan concurrently with other anticoagulant drugs. Do not use in horses with clotting disorders or within 24 hours of surgical procedures. Caution should be used when administering this drug before or after strenuous activities. Caution should be used when NSAIDS are administered concurrently due to the anticoagulant effects of Zycosan. If Zycosan and NSAIDS are used concurrently, horses should be monitored for hemorrhage or other clinical signs of abnormal bleeding. The safe use of Zycosan has not been evaluated in breeding, pregnant, or lactating horses. The safety of long-term repeat use of Zycosan has not been evaluated.
What to do if overdose?
Contact your nearest emergency animal hospital.
How can I store Zycosan (Pentosan Polysulfate Sodium Injection) 250 mg/mL, 7.5 mL vial?
Store at room temperature 68-77*F (20-25*C) with excursions between 59-86*F (15-30*C) permited.
Overview
Use as directed by your Veterinarian.
Administer 3mg/kg (1.4mg/lb) by intramuscular injection once weekly for four weeks (a total of four doses over 28 days)
Main Ingredients
250 mg/mL Pentosan Polysulfate Sodium