Legend 10mg/ml 4ml Vial RxBy Legend
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Legend is used to treat fetlock joint or carpus dysfunction, as well as inflammation of the joint lining. Horses are given this FDA-approved injectable drug intra-articularly or intravenously.
Who is Legend 10mg/ml 4ml Vial for?
Why use Legend 10mg/ml 4ml Vial?
Legend alleviates joint disease symptoms, decreases joint inflammation, and replenishes synovial joint fluid.
How does Legend 10mg/ml 4ml Vial work?
Legend contains sodium hyaluronate. Long chains of hyaluronate molecules create a filler network throughout the body. These are strewn around in normal cellular fluid. When injected into the joint pouch, hyaluronate sodium injections are believed to play a role in the healing of inflamed synovium. The synovial fluid, which is responsible for joint lubrication, is restored. It also adds to the viscoelastic qualities of regular joint fluid.
How is Legend 10mg/ml 4ml Vial sold?
Legend 10mg/ml 4ml Vial Legend 10mg/ml 4ml Box of 6 Vials
What are the side effects of Legend 10mg/ml 4ml Vial?
There was no evidence of local or systemic adverse responses in clinical field studies of intravenous and intra-articular injections.
What special precautions are there?
Take steps to assure sterility and use a cautious injection technique to avoid infection or edema, just as you would with any other intra-articular injection. Never provide an intra-articular injection to skin that has been exposed to a lot of counterirritant or scurf, or that has been recently fired or blistered. A radiographic examination should be performed on patients with acute laminitis to confirm that there are no significant joint fractures. This product has not been demonstrated or is not known to be safe for use in breeding animals. Keep out of the reach of children.
What to do if overdose?
If overdose occurs, please contact your local pet hospital or emergency pet clinic immediately.
How can I store Legend 10mg/ml 4ml Vial?
Never allow this product to exceed a temperature of 104 degrees Fahrenheit (40 degrees Celsius).
The synovial fluid contains significant quantities of hyaluronate. It is also found in the human body. This product includes hyaluronate, which is supposed to help control joint cells that cause inflammation. Hyaluronate begins to help in the repair of the joint lining and works to improve joint fluid thickness after injection. By cushioning and lubricating the joints, joint fluid preserves the joint lining.
After opening, any empty vials and unused vial contents should be thrown away. Allow for stall rest after treatment, then gradually return the horse to normal exercise. Use careful aseptic procedure while injecting intravenously, and inject gently into the jugular vein. Swelling may develop for a short period of time (24 to 48 hours) as a result of needle movement inside the joint area. Apply intra-articularly using careful aseptic approach, providing thorough animal restraint and disinfection. Before injecting, aseptically remove any extra joint fluid. Make sure the needle tip doesn't damage the cartilage's surface. This colorless, transparent solution is pyrogen-free, preservative-free, sterile, and has a low viscosity. 4mL intravenously or 2mL intra-articularly in the carpus or fetlock is the average suggested dose for horses. Re-treat once a week for a total of three times.
Hyaluronic acid, the conjugate acid of hyaluronate sodium, is extracted from the capsule of Streptococcus spp. and purified, resulting in a form which is essentially free of protein and nucleic acids.Legend Injectable Solution is supplied in 2 mL (20 mg) vials. Each mL contains: 10 mg hyaluronate sodium 8.5 mg sodium chloride 0.223 mg sodium phosphate dibasic 0.04 mg sodium phosphate monobasic The pH is adjusted to between 6.5 and 8.0 with sodium hydroxide or hydrochloric acid.