Estrumate (Cloprostenol Sodium) is a luteolysis-inducing intramuscular injectable solution. This medication's luteolytic activity makes it beneficial for managing the cow's estrous cycle, allowing for compliance with your management practices, treatment of particular extended luteal function-related diseases, and pregnancy termination when mismating has happened.
Who is Estrumate (Cloprostenol Sodium) for?
Beef and dairy cattle.
Why use Estrumate (Cloprostenol Sodium)?
Estrumate is a hormone that is used to treat diseases caused by extended luteal function and to regulate the estrous cycle in beef and dairy cattle.
How does Estrumate (Cloprostenol Sodium) work?
Cloprostenol sodium promotes corpus luteum regression, both functionally and morphologically. This impact on the corpus luteum generates estrus in normal cycle, non-pregnant animals within 2 to 5 days of treatment. Induction of luteolysis usually restores cyclicity and heals the disease in animals with pyometra (prolonged luteal function), mummified fetus, or luteal cysts. Pregnant animals may abort depending on the stage of pregnancy.
Merck Animal Health
(Cloprostenol Sodium) Prostaglandin Analogue for Cattle Equivalent to 250 mcg cloprostenol/mL
How is Estrumate (Cloprostenol Sodium) sold?
10 dose / 20 ml vial or 50 dose / 100 ml vial
What are the side effects of Estrumate (Cloprostenol Sodium)?
Minor side effects were noted in certain cattle treated at 50 and 100 times the recommended dose. These signs included: Milk Letdown Minor Frothing Uneasiness Do not use in pregnant animals, as the medication can cause abortion.
What special precautions are there?
If you're a woman of reproductive age, use great caution when handling this product. Handle with great caution if you have bronchial or respiratory problems. Avoid skin contact, and if it does happen, wash it off right away. This product quickly penetrates into the skin and has the potential to produce bronchospasm. Lower rates of conception should be anticipated when one product injection is used. If a fixed time breeding regimen is used and it omits a second insemination, lower rates of conception will occur. No effect on fertility will occur when the animal is bred 72 and 96 hours post-treatment, or when estrus is induced following treatment. If the animal develops an infection, antibiotics should be used. Prevent bacterial infections by using aseptic methods only, This product should only be used under the direction of a veterinarian. Keep out of the reach of children.
In case of overdose, immediately contact or get the animal to an emergency animal hospital. Another excellent resource is Merck Animal Health Pharmacovigilance. Their Livestock Technical Services may be reached at: 800-211-3573.
How can I store Estrumate (Cloprostenol Sodium)?
Use within 28 days of first use. Shield from light. Store in a dry and cool environment.
Do not use over 12 puncture stoppers. Administer an intramuscular injection of 2 mL in dairy or beef cattle. Follow your veterinarian's directions when administering this product.