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Item No.
32483
Prascend (pergolide tablets) for Horses 1 mg Rx
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Product Description
Prascend (pergolide tablets) is the #1 treatment approved by the FDA for Pituitary Pars Intermedia Dysfunction (PPID).4 Proven to improve clinical signs such as delayed shedding, muscle wasting, and abnormal sweating. Prascend helps horses with PPID have healthier, more comfortable lives. Prascend is a rectangular light red colored, half-scored tablet containing 1 mg pergolide, as pergolide mesylate, a dopamine receptor agonist for oral use in horses only.
Who is Prascend (pergolide tablets) for Horses 1 mg for?
Horses.
Why use Prascend (pergolide tablets) for Horses 1 mg?
Incorporating PRASCEND tablets into a PPID management protocol has been shown to reduce clinical signs of the disease and enhance horses’ overall quality of life. Clinical research and real-world evidence show that horses treated with PRASCEND:
• Are supported with the only therapy for PPID approved by the FDA.
• Showed improved clinical signs within 3 months, with continued improvement at 6 months.
• Experienced significant improvement in delayed shedding (89%), muscle wasting, abnormal fat distribution, and abnormal sweating within 6 months.
• Achieved a 76.1% overall treatment success rate based on clinical signs and endocrine testing.
• Sustained improvement and owner satisfaction in a long-term study, with 87% of owners reporting they would choose PRASCEND again for another PPID horse.
• Benefit from consistent, reliable dosing and potency, unlike compounded pergolide products, which have been shown to lose effectiveness rapidly.
How does Prascend (pergolide tablets) for Horses 1 mg work?
When a horse has PPID, the pituitary gland overproduces hormones, making it difficult to keep bodily functions in a healthy working state, resulting in a variety of clinical signs. Prascend tablets act to curb the overproduction and secretion of these hormones to better control clinical signs.
Manufacturer:
Boehringer Ingelheim
Active Ingredients(s):
Pergolide, as pergolide mesylate
How is Prascend (pergolide tablets) for Horses 1 mg sold?
Prascend (pergolide tablets) are available in 1 mg strength – packaged 10 tablets per blister and 60 or 160 tablets per carton.
What are the side effects of Prascend (pergolide tablets) for Horses 1 mg?
The most common adverse effect is decreased appetite, which is typically mild. If severe, your veterinarian may recommend a temporary dose adjustment.
What special precautions are there?
Warnings:
• Not for use in horses intended for human consumption.
• PRASCEND® tablets should not be crushed due to the potential for increased human exposure.
• Keep in a secure location out of reach of dogs, cats, and other animals to prevent accidental ingestion or overdose. Dogs have eaten PRASCEND tablets dropped during administration.
• Adverse reactions may occur if animals other than horses ingest PRASCEND tablets.
• Contraindicated in horses with hypersensitivity to pergolide mesylate or other ergot derivatives.
US-EQU-0392-2025
Caution/Precautions:
Treatment with PRASCEND® (pergolide tablets) may cause inappetence. The use of PRASCEND in breeding, pregnant, or lactating horses has not been evaluated. The effects of pergolide mesylate on breeding, pregnant, or lactating horses are not known; however, the pharmacologic action of pergolide mesylate suggests that it may interfere with reproductive functions such as lactation.
PRASCEND is approximately 90% associated with plasma proteins. Use caution if administering PRASCEND with other drugs that affect protein binding. Dopamine antagonists, such as neuroleptics (phenothiazines, domperidone) or metoclopramide,
ordinarily should not be administered concurrently with PRASCEND (a dopamine agonist) since these agents may diminish the effectiveness of PRASCEND tablets.
Keep PRASCEND in a secure location out of reach of dogs, cats, and other animals to prevent accidental ingestion or overdose. Dogs have eaten PRASCEND tablets that were placed in food intended for horses or dropped during administration of the tablets to the horses.
Adverse reactions may occur if animals other than horses ingest PRASCEND tablets.
PRASCEND is contraindicated in horses with hypersensitivity to pergolide mesylate or other ergot derivatives.
What to do if overdose?
Contact your closest emergency pet hospital.
How can I store Prascend (pergolide tablets) for Horses 1 mg?
Store at or below 25°C (77°F).
Overview
To obtain an individual response, the lowest effective dosage should be used. For precise dosage, tablets are scored. To the closest half-tablet increment, calculate your horse's dose. This drug should not be crushed. Crushed tablets should not be consumed by humans. Orally, at a starting dose of 2g per kg of body weight, one time per day. Adjust until you get the desired result, but don't go beyond 4g per kilogram per day. Reduce the dose by half for three to five days if the horse appears to be developing an intolerance, then gradually increase at a rate of 2mcg per kg of body weight every two weeks until the desired effect is achieved. Dosing Recommendations: 300 - 749 Lbs: 1/2 to 1 Tablet 750 - 1249 Lbs: 1 to 2 Tablets 1250 - 1749 Lbs: 1 1/2 to 3 Tablets 1750 - 2249 Lbs: 2 to 4 Tablets
Main Ingredients
Prascend Tablets contain 1 mg pergolide, as pergolide mesylate. Pergolide mesylate is a synthetic ergot derivative and is a potent dopamine receptor agonist. The chemical name of pergolide mesylate is 8β-[(Methylthio) methyl]-6-propylergoline monomethanesulfonate.