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Item No.
52748
Maropitant Citrate Tablets Rx
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Product Description
Maropitant Citrate tablets are a prescription medication indicated for the prevention of acute vomiting and the prevention of vomiting due to motion sickness in dogs.
Who is Maropitant Citrate Tablets for?
For Dogs ages 16 weeks and up.
Why use Maropitant Citrate Tablets?
Helps prevent vomiting in dogs. Easy to administer tablets. Non-sedative.
How does Maropitant Citrate Tablets work?
Maropitant is a neurokinin 1 (NK1) receptor antagonist which acts by inhibiting the binding of substance P, a neuropeptide of the tachykinin family. Substance P is found in significant concentrations in the nuclei comprising the emetic center and is considered the key neurotransmitter involved in emesis.1 By inhibiting the binding of substance P within the emetic center, maropitant provides broad-spectrum effectiveness against neural (central) and humoral (peripheral) causes of vomiting.
Manufacturer:
Zyvet Animal Health
Active Ingredients(s):
Maropitant Citrate
How is Maropitant Citrate Tablets sold?
Sold as 4 tablets in a blister pack in the following strengths: 16 mg, 24 mg, 60 mg, or 160 mg.
What are the side effects of Maropitant Citrate Tablets?
The following adverse events reported for dogs are listed in decreasing order of frequency: anorexia, depression/lethargy, hypersalivation, vomiting, diarrhea, trembling, ataxia, allergic reactions, weight loss, convulsion, hyperactivity, and panting.
What special precautions are there?
WARNINGS:
Not for use in humans. Keep out of the reach of children. In case of accidental ingestion, seek medical advice. Topical exposure may elicit localized allergic skin reactions in some individuals. Repeated or prolonged exposure may lead to skin sensitization. Wash hands with soap and water after administering drug. Maropitant Citrate is also an ocular irritant. In case of accidental eye exposure, flush with water for 15 minutes and seek medical attention.
Keep Maropitant Citrate Tablets in a secure location out of reach of dogs, cats, and other animals to prevent accidental ingestion or overdose.
In puppies younger than 11 weeks of age, histological evidence of bone marrow hypocellularity was observed at higher frequency and greater severity in puppies treated with Maropitant Citrate compared to control puppies. In puppies 16 weeks and older, bone marrow hypocellularity was not observed (see ANIMAL SAFETY).
PRECAUTIONS:
The safe use of Maropitant Citrate tablets has not been evaluated in dogs used for breeding, or in pregnant or lactating bitches.
The safe use of Maropitant Citrate has not been evaluated in dogs with gastrointestinal obstruction, or dogs that have ingested toxins.
Use with caution in dogs with hepatic dysfunction because Maropitant Citrate is metabolized by CYP3A enzymes (see Pharmacokinetics).Use with caution with other medications that are highly protein bound. The concomitant use of Maropitant Citrate with other protein bound drugs has not been studied in dogs. Commonly used protein bound drugs include NSAIDs, cardiac, anticonvulsant, and behavioral medications.
What to do if overdose?
Contact your nearest emergency animal hospital.
How can I store Maropitant Citrate Tablets?
Store at controlled room temperature 20°-25°C (68°-77°F), excursions permitted to 40°C (104°F).
Overview
Use as directed by your Veterinarian.
DOSAGE AND ADMINISTRATION:
For Prevention of Acute Vomiting in dogs 2 -7 months of age: Administer Maropitant Citrate tablets orally at a minimum dose of
2 mg/kg (0.9 mg/lb) body weight once daily for up to 5 consecutive days (see WARNINGS and Animal Safety).
For Prevention of Acute Vomiting in dogs 7 months of age and older: Administer Maropitant Citrate tablets orally at a minimum dose of 2 mg/kg (0.9 mg/lb) body weight once daily until resolution of acute vomiting.
If vomiting persists despite treatment, the case should be re-evaluated. Maropitant Citrate is most effective in preventing acute vomiting associated with chemotherapy if administered prior to the chemotherapeutic agent.
Main Ingredients
Active Ingredient: Maropitant Citrate
